To strengthen the advantages of 3D bioprinting, Cellink acquires Nanoscribe, a 3D micro-nano printer manufacturer

China and Africa News, June 2nd, Swedish bioprinting pioneer Cellink said that it will acquire Nanoscribe through cash and stock worth up to 50 million euros. Including cash, stocks, and performance. After the transaction is completed, CELLINK will fully control Nanoscribe while integrating 2PP technology into its own technology to create a more realistic soft tissue. Utilizing the new micro-nano-level 3D printing function will expand the usage of consumables and shorten the delivery time and cost of 3D printed products.

CELLINK paid for the value of 50 million euros to purchase all the outstanding shares of Nanoscribe in a cashless and debt-free manner. According to the cash and stock acquisition agreement reached by the two companies, Cellink will first pay the first 34 million euros, and if Nanoscribe achieves its financial goals later, it will receive another 16 million euros. Of the purchase price, 22.1 million euros will be paid in cash; of which 11.9 million euros will be provided in the form of newly issued shares; 16 million euros will be paid through performance-related earnings, depending on whether the company can achieve 2021-2023 Depends on financial goals for the year.

After the transaction is completed, Nanoscribe will maintain the same brand and leadership position, and financial data will be merged into CELLINK from the second quarter of 2021. Nanoscribe expects a turnover of 15.4 million euros in fiscal 2021 and will maintain growth. CELLINK expects to receive revenue from new implants, microneedles, membranes and omics consumables production lines.

Nanoscribe was founded in 2007 by scientists from the Karlsruhe Institute of Technology (KIT). Nanoscribe specializes in the development of nano, micro and mesoscale 3D printers and materials. The company’s proprietary 2PP technology can manufacture tiny ultra-high-resolution objects with details up to 200 nanometers, which has great potential in optical and Electronic applications. Nanoscribe is a technology company derived from the Karlsruhe Institute of Technology (KIT). Nanoscribe has developed a two-photon polymerization technology for manufacturing complex microstructures.

If the acquisition proceeds as expected, Nanoscribe will work with several other companies recently acquired by Cellink to jointly build a series of cutting-edge technology portfolios that will revolutionize the biological and medical industries.

Cellink said: “The life sciences industry is undergoing very exciting changes. Consumables and reagents are the main bottleneck for medical applications such as sequencing. Therefore, many processes and technologies are being miniaturized to increase throughput and reduce costs. For example, single-cell genomes. This is the case for sample preparation for scientific applications. With Nanoscribe’s two-photon polymerization technology, we have maintained our competitiveness in this transformation process, allowing us to miniaturize our devices for wider applications.”

CELLINK CEO Erik Gatenholm said: “With Nanoscribe’s advanced 2PP technology, we will complement our product portfolio and provide more products to our outstanding customers.” “We will combine a strong, goal-oriented growth agenda with Combining pioneering bio-fusion technologies to improve the health of the world.”

Print the vascular microenvironment

More specifically, Cellink said that the acquisition will make it the only company in the life sciences industry with its own two-photon polymerization additive manufacturing capabilities, providing it with a significant competitive advantage.

Cellink said: “Nanoscribe’s technology can bioprint the vascular microenvironment on a subcellular scale, which is very suitable for cell research and laboratory-on-a-chip applications.”

This manufacturing capability will help Cellink’s broader product development and provide the company with new revenue growth points by manufacturing various implants, microneedles, microporous membranes and other consumables for bioomics applications.

Among them, the key application area worthy of attention is structural bioprinting. Nanoscribe’s ultrafast laser-based printing equipment can build more realistic tissue structures, including angiogenesis.

Cellink CEO Erik Gatenholm said in a statement: “With Nanoscribe’s two-photon polymerization technology, our product portfolio is strongly complemented, allowing us to provide customers with a wider range of products. This acquisition sets our strong goal A combination of driven growth, combined with pioneering bio-convergence technologies, to improve medical and health applications worldwide.”

As early as 2007, Martin Hermatschweiler co-founded Nanoscribe with KIT scientists and PhDs. He said: “The most advanced two-photon polymerization technology that we have always been proud of provides customers with tools to realize their breakthrough ideas. We I very much look forward to joining the Cellink Group and jointly exploring more possibilities of optical gemini polymerization technology.”

Support behind Zeiss

Since the birth of Nanoscribe, the company has used two-photon polymerization technology to make some very eye-catching miniature replicas of the Statue of Liberty, Eiffel Tower, Empire State Building, etc., which have attracted widespread attention from the photonics industry.

Optical giant Zeiss was one of Nanoscribe’s early investors. The two companies expanded their partnership in 2018 through a $30 million KIT startup innovation park, which is now Nanoscribe’s headquarters.

Nanoscribe’s Photonic Professional GT2 is the world’s most accurate 3D micro-nano printer. This equipment perfectly combines the extremely high-precision technical characteristics of two-photon polymerization with cross-scale microscopic 3D printing, and is suitable for rapid prototyping at the nanometer, micrometer, and centimeter levels.

In 2014, the predecessor of this device won the Photonics Prism Award in the “Advanced Manufacturing” category.

Applications in the field of micromachines and MEMS

Nanoscribe’s Photonic Professional GT2 two-photon maskless lithography system is designed with versatility and wide selection of printing materials, enabling the production of micromechanical components, such as printing with photopolymers, nanoparticle composites, or hydrogels The remote control of the mobile micro-robot, and can choose to add metal coating. In addition, micro-nano devices can also be printed directly on different substrates, and even on micro-electromechanical systems (MEMS).

Nanoscribe recently revealed that Nanoscribe, as a member of the EU’s photonic computing project PHOENICS, has joined hands with the University of Munster in Germany to launch a four-year scientific research project with the world’s leading photonic computing field to achieve ultra-high broadband and energy-efficient gigabit Computational processing capabilities, a computing platform for the new generation of artificial intelligence (AI) applications.

The Links:   G090VTN020 MCD312-16IO1

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